Autophagy Machinary Components:
Genes Involved in Autophagic Vacuole Formation:
Ambra1, Atg12, Atg16l1, Atg4a, Atg4b, Atg4c, Atg4d, Atg5, Atg9a, Atg9b,
Becn1, Gabarap, Gabarapl1, Gabarapl2, Irgm, Map1lc3a, Map1lc3b, Rgs19,
Ulk1.
Genes Responsible for Protein Targeting to Membrane / Vacuole: Atg4a, Atg4b, Atg4c, Atg4d, Gabarap.
Genes Responsible for Protein Transport: Atg10, Atg16l1, Atg16l2, Atg3, Atg4a, Atg4b, Atg4c, Atg4d, Atg7, Atg9a, Gabarap, Gabarapl2, Rab24.
Genes Linking Autophagosome to Lysosome: 1200002N14Rik, Gabarap, Tmem166.
Genes Involved in Protein Ubiquitination: Atg3, Atg7.
Genes with Protease Activity: Atg4a, Atg4b, Atg4c, Atg4d.
Regulation of Autophagy:
Co-Regulators of Autophagy and Apoptosis:
1200002N14Rik, Akt1, App, Atg12, Atg5, Bad, Bak1, Bax, Bcl2, Bcl2l1,
Becn1, Bid, Bnip3, Casp3, Casp8, Cdkn1b, Cdkn2a, Cln3, Ctsb, Cxcr4,
Dapk1, Eif2ak3, Fadd, Fas, Hdac1, Htt, Ifna2, Ifng, Igf1, Ins2, Mapk8,
Nfkb1, Pik3cg, Prkaa1, Pten, Snca, Sqstm1, Tgfb1, Tgm2, Tnf, Tnfsf10,
Trp53, Trp73.
Co-Regulators of Autophagy and the Cell Cycle: Bax, Cdkn1b, Cdkn2a, Ifng, Pten, Rb1, Tgfb1, Trp53, Trp73.
Autophagy Induction by Intracellular Pathogens: Eif2ak3, Ifna2, Ifna4, Ifng.
Autophagy in Response to Other Intracellular Signals: Arsa, Ctss, Eif4g1, Esr1, Gaa, Hgs, Mapk14, Pik3c3, Pik3r4, Prkaa2, Rps6kb1, Tmem74, Tmem77, Ulk2, Uvrag.
Chaperone-Mediated Autophagy: Hsp90aa1, Hspa8.
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